Geriatric care includes the prevention and diagnosis of diseases, as well as the management of diseases, disabilities, and other health concerns in individuals ≥ 65 years of age. Special consideration is given when addressing multiple aspects that are specific to ageing. Preventive measures such as vaccinations as well as cancer and disease screeningScreeningPreoperative Care are essential in this age group because of the high risk for infectionsInfectionsInvasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.Chronic Granulomatous Disease and developing cancer and chronic diseases. A majority of older individuals have at least 1 chronic medical condition, which increases the likelihood of polypharmacy and adverse drug reactions. VisionVisionOphthalmic Exam, hearing, cognitive function, gaitGaitManner or style of walking.Neurological Examination, and balance are among the functions that decline in the geriatric populationGeriatric PopulationGeriatric Care and Screening. These disease- and age-related factors affect the activities of daily living. As such, fall risk should be assessed in all vulnerable individuals. Assessing the financial and social resources of older adults is also important, given the direct impact of these factors on their health. A multidisciplinary approach involving various professionals in the healthcare field is important in achieving comprehensive care for older adults.
In the US, over 20% of the population will be > 65 years of age by 2030.
Many factors affect the functional status of individuals in this age group:
80% of individuals have at least 1 chronic condition and 50% have at least 2 chronic conditions.
Declines in visionVisionOphthalmic Exam, hearing, balance, and cognition may impair function.
Apart from addressing chronic conditions, comprehensive preventive care with functional and psychosocial evaluation are essential in improving geriatric well-being.
Assessment of older adults[19]
Care for older adults is a team-based approach that involves various professionals (e.g., physiciansPhysiciansIndividuals licensed to practice medicine.Clinician–Patient Relationship, social workers, nutritionists, physical therapists) working together to assess the following:
Physical health:
Address and manage current chronic conditions (e.g., heart failureHeart FailureA heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (ventricular dysfunction), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as myocardial infarction.Total Anomalous Pulmonary Venous Return (TAPVR), hypertensionHypertensionHypertension, or high blood pressure, is a common disease that manifests as elevated systemic arterial pressures. Hypertension is most often asymptomatic and is found incidentally as part of a routine physical examination or during triage for an unrelated medical encounter. Hypertension, diabetesDiabetesDiabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin. Type 1 DM is diagnosed mostly in children and young adults as the result of autoimmune destruction of β cells in the pancreas and the resulting lack of insulin. Type 2 DM has a significant association with obesity and is characterized by insulin resistance.Diabetes Mellitus, CKDCKDChronic kidney disease (CKD) is kidney impairment that lasts for ≥ 3 months, implying that it is irreversible. Hypertension and diabetes are the most common causes; however, there are a multitude of other etiologies. In the early to moderate stages, CKD is usually asymptomatic and is primarily diagnosed by laboratory abnormalities.Chronic Kidney Disease).
Check for cognitive decline and memoryMemoryComplex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.Psychiatric Assessment disturbances.
Depression may go undetected, as symptoms present in atypical ways.
SuicideSuicideSuicide is one of the leading causes of death worldwide. Patients with chronic medical conditions or psychiatric disorders are at increased risk of suicidal ideation, attempt, and/or completion. The patient assessment of suicide risk is very important as it may help to prevent a serious suicide attempt, which may result in death. Suicide rate is higher in older adults than in the general population.
Proceed with workup of unintentional weight lossWeight lossDecrease in existing body weight.Bariatric Surgery based on presentation (e.g., labs, imaging studies, and cancer screeningScreeningPreoperative Care, if not yet completed).
Alcohol, tobacco, and substance use[5]
Alcohol use:
Approximately 50% of adults > 65 years of age consume alcohol.
Alcohol use in older adults is associated with:
Increased risk of falls
Negative effects on function, cognition, and general overall health
The American Geriatrics Society recommends asking older adults specific questions regarding the frequency and quantity of alcohol consumption.
The CAGE questionnaire asks the patient if they have:
Felt they should Cut down on their alcohol intake?
Been Annoyed by people criticizing their drinking?
Felt Guilty about drinking?
Had a drink first thing in the morning (Eye opener) for shakiness or a hangover?
A total score of ≥ 2 is clinically significant; it is appropriate to counsel the patient regarding alcohol intake and its adverse effects.
Tobacco use:
Older adults should be asked about tobacco use.
If current smokers, counselling on smokingSmokingWillful or deliberate act of inhaling and exhaling smoke from burning substances or agents held by hand.Interstitial Lung Diseases cessation and methods of quitting should be offered.
Marijuana/cannabis use:[22,23]
The legal landscape is changing rapidly; marijuana is now legal in most states to varying extents.
It remains a Schedule 1 drug (medical use is not recognized and is considered a substance at high risk for abuse) under US federal law.
Older patientsPatientsIndividuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures.Clinician–Patient Relationship use many forms of marijuana besides smokingSmokingWillful or deliberate act of inhaling and exhaling smoke from burning substances or agents held by hand.Interstitial Lung Diseases (e.g., oral, topical, cannabidiolCannabidiolCompound isolated from cannabis sativa extract.Cannabinoids (CBDCBDAtypical Parkinsonian Syndromes) supplements) and may not volunteer this information unless asked.
Can cause tachycardiaTachycardiaAbnormally rapid heartbeat, usually with a heart rate above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.Sepsis in Children, increased blood pressure, or orthostatic hypotensionOrthostatic hypotensionA significant drop in blood pressure after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm hg decrease in systolic pressure or a 10-mm hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include dizziness, blurred vision, and syncope.Hypotension in older adults
Associated with increased risk of mental and physical health issues and cannabis use disorderCannabis use disorderCannabis use disorder (CUD) is characterized by the pathologic consumption of cannabis, which is the most commonly used illicit substance worldwide. While cannabis has some beneficial medical uses, it also has the potential to cause intoxication characterized by psychosis or cognitive impairment, especially in chronic use. Cannabis Use Disorder in older adults
Physical activity[8]
Exercise is recommended for all adults and is associated with better overall health, decreased healthcare costs, and fewer mobility limitationsLimitationsConflict of Interest.
Generally, the American Heart AssociationAmerican Heart AssociationA voluntary organization concerned with the prevention and treatment of heart and vascular diseases.Heart Failure recommends the following regimen for adults:
At least 150 minutes of moderate-intensity exercise every week OR
75 minutes of vigorous activity 3 days a week
Strength training (e.g., weight training, resistanceResistancePhysiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow.Ventilation: Mechanics of Breathing training, or weight-bearing calisthenics) to maintain or improve strength
A gradual increase in time and intensity is recommended.
Routine testing such as ECGECGAn electrocardiogram (ECG) is a graphic representation of the electrical activity of the heart plotted against time. Adhesive electrodes are affixed to the skin surface allowing measurement of cardiac impulses from many angles. The ECG provides 3-dimensional information about the conduction system of the heart, the myocardium, and other cardiac structures. Electrocardiogram (ECG) or stress testing is not recommended for asymptomatic older adults prior to initiating an exercise program.
Medical clearance is recommended prior to commencing an exercise program:
In symptomatic individuals (e.g., with a complaint of chest painPainAn unpleasant sensation induced by noxious stimuli which are detected by nerve endings of nociceptive neurons.Pain: Types and Pathways or dyspneaDyspneaDyspnea is the subjective sensation of breathing discomfort. Dyspnea is a normal manifestation of heavy physical or psychological exertion, but also may be caused by underlying conditions (both pulmonary and extrapulmonary). Dyspnea)
In individuals with known heart disease or with renal or metabolic disease (factoring in the desired exercise intensity)
Medication Management
Considerations[11]
Age-related changes can affect drug absorptionAbsorptionAbsorption involves the uptake of nutrient molecules and their transfer from the lumen of the GI tract across the enterocytes and into the interstitial space, where they can be taken up in the venous or lymphatic circulation.Digestion and Absorption, distribution, metabolism, and excretion as well as physiologic effects in older adults:
The volume of distribution may increase with age, secondary to a relative increase in body fat and a decrease in leanLEANQuality Measurement and Improvement muscle massMassThree-dimensional lesion that occupies a space within the breastImaging of the Breast.
Drug metabolism may be impaired by a decline in hepatic function.
Decreased drug clearance due to a natural, age-related decline in renal function
Increased sensitivity to the effects of a medication may be seen with increasing age.
Caution with polypharmacy (the use of 5–10+ medications), which is associated with:
↑ Risk of adverse events and falls
↑ Risk of hospital admissions
↓ Physical and cognitive functioning
Monitor for drug-drug interactions and adverse effects:
Ask about herbal medicines, supplements, and over-the-counter medications due to potential interactions.
Closely monitor for adverse effects when initiating a new medication.
Avoid “prescribing cascades” (adding a medication to treat adverse effects of another medication)
Provides a list of drugs that can pose a risk to older adults due to adverse effects, drug-drug interactions, and drug dose adjustments; updated every 3 years
Table: Medications that are potentially inappropriate for older adults
Medications
Side effects
Antipsychotics
Associated with a high risk of falling and fractureFractureA fracture is a disruption of the cortex of any bone and periosteum and is commonly due to mechanical stress after an injury or accident. Open fractures due to trauma can be a medical emergency. Fractures are frequently associated with automobile accidents, workplace injuries, and trauma.Overview of Bone Fractures
Higher risk of mortalityMortalityAll deaths reported in a given population.Measures of Health Status when used for behavioral control in dementiaDementiaMajor neurocognitive disorders (NCD), also known as dementia, are a group of diseases characterized by decline in a person’s memory and executive function. These disorders are progressive and persistent diseases that are the leading cause of disability among elderly people worldwide.Major Neurocognitive Disorders
Glyburide
Long-acting sulfonylurea associated with a high risk of hypoglycemiaHypoglycemiaHypoglycemia is an emergency condition defined as a serum glucose level ≤ 70 mg/dL (≤ 3.9 mmol/L) in diabetic patients. In nondiabetic patients, there is no specific or defined limit for normal serum glucose levels, and hypoglycemia is defined mainly by its clinical features. Hypoglycemia
BenzodiazepinesBenzodiazepinesBenzodiazepines work on the gamma-aminobutyric acid type A (GABAA) receptor to produce inhibitory effects on the CNS. Benzodiazepines do not mimic GABA, the main inhibitory neurotransmitter in humans, but instead potentiate GABA activity. Benzodiazepines
Increased risk of deliriumDeliriumDelirium is a medical condition characterized by acute disturbances in attention and awareness. Symptoms may fluctuate during the course of a day and involve memory deficits and disorientation. Delirium, sedation, and falls
OpioidsOpioidsOpiates are drugs that are derived from the sap of the opium poppy. Opiates have been used since antiquity for the relief of acute severe pain. Opioids are synthetic opiates with properties that are substantially similar to those of opiates. Opioid Analgesics
Increased risk of deliriumDeliriumDelirium is a medical condition characterized by acute disturbances in attention and awareness. Symptoms may fluctuate during the course of a day and involve memory deficits and disorientation. Delirium, sedation, falls, constipationConstipationConstipation is common and may be due to a variety of causes. Constipation is generally defined as bowel movement frequency < 3 times per week. Patients who are constipated often strain to pass hard stools. The condition is classified as primary (also known as idiopathic or functional constipation) or secondary, and as acute or chronic. Constipation, urinary retentionUrinary retentionInability to empty the urinary bladder with voiding (urination).Delirium, and respiratory depression
AnticholinergicsAnticholinergicsAnticholinergic drugs block the effect of the neurotransmitter acetylcholine at the muscarinic receptors in the central and peripheral nervous systems. Anticholinergic agents inhibit the parasympathetic nervous system, resulting in effects on the smooth muscle in the respiratory tract, vascular system, urinary tract, GI tract, and pupils of the eyes. Anticholinergic Drugs (includes some antidepressants and antihistaminesAntihistaminesAntihistamines are drugs that target histamine receptors, particularly H1 and H2 receptors. H1 antagonists are competitive and reversible inhibitors of H1 receptors. First-generation antihistamines cross the blood-brain barrier and can cause sedation. Antihistamines)
Increased risk of deliriumDeliriumDelirium is a medical condition characterized by acute disturbances in attention and awareness. Symptoms may fluctuate during the course of a day and involve memory deficits and disorientation. Delirium, sedation, falls, constipationConstipationConstipation is common and may be due to a variety of causes. Constipation is generally defined as bowel movement frequency < 3 times per week. Patients who are constipated often strain to pass hard stools. The condition is classified as primary (also known as idiopathic or functional constipation) or secondary, and as acute or chronic. Constipation, and urinary retentionUrinary retentionInability to empty the urinary bladder with voiding (urination).Delirium
Increased risk of GI bleeding, especially with concomitant anticoagulantsAnticoagulantsAnticoagulants are drugs that retard or interrupt the coagulation cascade. The primary classes of available anticoagulants include heparins, vitamin K-dependent antagonists (e.g., warfarin), direct thrombin inhibitors, and factor Xa inhibitors. Anticoagulants
Increased risk of renal impairment
Possible cardiovascular risk
α-Blockers
Increased risk of hypotensionHypotensionHypotension is defined as low blood pressure, specifically < 90/60 mm Hg, and is most commonly a physiologic response. Hypotension may be mild, serious, or life threatening, depending on the cause. Hypotension
PPIs*
Increased risk of Clostridium difficileClostridium difficileA common inhabitant of the colon flora in human infants and sometimes in adults. The type species clostridioides difficile is formerly known as Clostridium difficile. It is a causative agent for clostridioides infections and is associated with pseudomembranous enterocolitis in patients receiving antibiotic therapy.ClostridiainfectionsInfectionsInvasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.Chronic Granulomatous Disease
Increased risk of vitamin B12Vitamin B12A cobalt-containing coordination compound produced by intestinal microorganisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. Intrinsic factor is important for the assimilation of vitamin B 12.Folate and Vitamin B12malabsorptionMalabsorptionGeneral term for a group of malnutrition syndromes caused by failure of normal intestinal absorption of nutrients.Malabsorption and Maldigestion
Screenings in the older population should consider risk factors beyond merely the individual’s age. The individual and/or caregivers should be involved in decision-making about pursuing screeningScreeningPreoperative Care. ScreeningScreeningPreoperative Care tests are generally not indicated if the life expectancyLife expectancyBased on known statistical data, the number of years which any person of a given age may reasonably expected to live.Population Pyramids is < 5 years.
Men between 65 and 75 years of age with a history of tobacco use should undergo abdominal ultrasound screeningScreeningPreoperative Care once.
Breast cancerBreast cancerBreast cancer is a disease characterized by malignant transformation of the epithelial cells of the breast. Breast cancer is the most common form of cancer and 2nd most common cause of cancer-related death among women. Breast Cancer[3,13]
Based on the US Preventive Services Task Force (USPSTF):
Women > 75 years of age: insufficient evidence to support screeningScreeningPreoperative Care (American Cancer Society suggests the option of screeningScreeningPreoperative Care if life expectancyLife expectancyBased on known statistical data, the number of years which any person of a given age may reasonably expected to live.Population Pyramids > 10 years)
The 1st image shows mammography of normal breast tissue; the 2nd image shows cancerous breast tissue. Mammography is done for early detection of breast cancer.
Image: “Mammo breast cancer” by National Cancer Institute. License: Public Domain
Cardiovascular disease[18,25]
ScreeningScreeningPreoperative Care for hypertensionHypertensionHypertension, or high blood pressure, is a common disease that manifests as elevated systemic arterial pressures. Hypertension is most often asymptomatic and is found incidentally as part of a routine physical examination or during triage for an unrelated medical encounter. Hypertension:
HypertensionHypertensionHypertension, or high blood pressure, is a common disease that manifests as elevated systemic arterial pressures. Hypertension is most often asymptomatic and is found incidentally as part of a routine physical examination or during triage for an unrelated medical encounter. Hypertension is a major risk factor for ischemic heart diseaseIschemic heart diseaseCoronary heart disease (CHD), or ischemic heart disease, describes a situation in which an inadequate supply of blood to the myocardium exists due to a stenosis of the coronary arteries, typically from atherosclerosis. Coronary Heart Disease and stroke.
USPSTF: check blood pressure annually in all adults > 18 years of age
Confirm diagnosis with outside blood pressure measurements (before initiation of treatment).
ScreeningScreeningPreoperative Care for diabetesDiabetesDiabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin. Type 1 DM is diagnosed mostly in children and young adults as the result of autoimmune destruction of β cells in the pancreas and the resulting lack of insulin. Type 2 DM has a significant association with obesity and is characterized by insulin resistance.Diabetes Mellitus mellitus:
Part of cardiovascular risk assessmentRisk assessmentThe qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences.Preoperative Care
The USPSTF recommends diabetes screeningDiabetes ScreeningAdult Health Maintenance for individuals who are 35–70 years of age and those who are overweight or obese (BMIBMIAn indicator of body density as determined by the relationship of body weight to body height. Bmi=weight (kg)/height squared (m2). Bmi correlates with body fat (adipose tissue). Their relationship varies with age and gender. For adults, bmi falls into these categories: below 18. 5 (underweight); 18. 5-24. 9 (normal); 25. 0-29. 9 (overweight); 30. 0 and above (obese).Obesity ≥ 25).
Fasting glucoseGlucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.Lactose Intolerance or HbA1cHbA1cProducts of non-enzymatic reactions between glucose and hemoglobin a, occurring as a minor fraction of the hemoglobin components of human erythrocytes. Hemoglobin a1c is hemoglobin a with glucose covalently bound to the terminal valine of the beta chain. Glycated hemoglobin a is used as an index of the average blood sugar level over a lifetime of erythrocytes.Diabetes MellitusscreeningScreeningPreoperative Care (abnormal result needs a repeat test for confirmation, unless both are done at the same time)
Those found to have prediabetes should be educated about preventive interventionsPreventive interventionsPreventive interventions are actions that prevent a disease and reduce the incidence of new cases, including education, vaccines, nutritional interventions, maternal and neonatal interventions, behavioral interventions, and environmental interventions.Points of Intervention.
The 2019 American College of Cardiology/American Heart AssociationAmerican Heart AssociationA voluntary organization concerned with the prevention and treatment of heart and vascular diseases.Heart Failure (ACC/AHA) guideline recommends:[25]
Routine assessment of cardiovascular risk factors in adults 40–75 years of age, which includes calculation of the 10-year risk of ASCVD
Statin therapy for primary prevention of ASCVD in adults 40–75 years of age with low-density lipoproteinLow-density lipoproteinA class of lipoproteins of small size (18-25 nm) and light (1. 019-1. 063 g/ml) particles with a core composed mainly of cholesterol esters and smaller amounts of triglycerides. The surface monolayer consists mostly of phospholipids, a single copy of apolipoprotein B-100, and free cholesterol molecules. The main ldl function is to transport cholesterol and cholesterol esters to extrahepatic tissues.Cholesterol MetabolismcholesterolCholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.Cholesterol Metabolism levels ≥ 190 mg/dL, with diabetesDiabetesDiabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin. Type 1 DM is diagnosed mostly in children and young adults as the result of autoimmune destruction of β cells in the pancreas and the resulting lack of insulin. Type 2 DM has a significant association with obesity and is characterized by insulin resistance.Diabetes Mellitus mellitus and those determined to have elevated risk as determined by their 10-year ASCVD risk calculation
Individualized discussion on whether to continue statin therapy after age 75
The USPSTF recommends statin therapy for primary prevention of ASCVD in adults 40–75 years of age who have ≥ 1 CVD risk factor (e.g., hypertensionHypertensionHypertension, or high blood pressure, is a common disease that manifests as elevated systemic arterial pressures. Hypertension is most often asymptomatic and is found incidentally as part of a routine physical examination or during triage for an unrelated medical encounter. Hypertension, diabetesDiabetesDiabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin. Type 1 DM is diagnosed mostly in children and young adults as the result of autoimmune destruction of β cells in the pancreas and the resulting lack of insulin. Type 2 DM has a significant association with obesity and is characterized by insulin resistance.Diabetes Mellitus) and a 10-year risk of a cardiovascular event of ≥ 10%.[30]
AspirinAspirinThe prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis.Nonsteroidal Antiinflammatory Drugs (NSAIDs) use is considered on a case-to-case basis (due to the risk of bleeding).
Cervical cancerCervical cancerCervical cancer, or invasive cervical carcinoma (ICC), is the 3rd most common cancer in women in the world, with > 50% of the cases being fatal. In the United States, ICC is the 13th most common cancer and the cause of < 3% of all cancer deaths due to the slow progression of precursor lesions and, more importantly, effective cancer screening. Cervical Cancer[4]
Population at risk:
Up to 65 years of age, the options are:
Cervical cytologyCervical cytologyA procedure in which ectocervical and endocervical cells are collected to evaluate the transformation zone (area at risk for cervical cancer).Cervical Cancer Screening every 3 years
High-risk HPVHPVHuman papillomavirus (HPV) is a nonenveloped, circular, double-stranded DNA virus belonging to the Papillomaviridae family. Humans are the only reservoir, and transmission occurs through close skin-to-skin or sexual contact. Human papillomaviruses infect basal epithelial cells and can affect cell-regulatory proteins to result in cell proliferation. Papillomavirus (HPV) (hrHPV) screeningScreeningPreoperative Care every 5 years
2 consecutive negative Pap and HPVHPVHuman papillomavirus (HPV) is a nonenveloped, circular, double-stranded DNA virus belonging to the Papillomaviridae family. Humans are the only reservoir, and transmission occurs through close skin-to-skin or sexual contact. Human papillomaviruses infect basal epithelial cells and can affect cell-regulatory proteins to result in cell proliferation. Papillomavirus (HPV) test results within the past 10 years, with the most recent test within the past 5 years
If adequate screeningScreeningPreoperative Care has not been performed, provide cytology/HPVHPVHuman papillomavirus (HPV) is a nonenveloped, circular, double-stranded DNA virus belonging to the Papillomaviridae family. Humans are the only reservoir, and transmission occurs through close skin-to-skin or sexual contact. Human papillomaviruses infect basal epithelial cells and can affect cell-regulatory proteins to result in cell proliferation. Papillomavirus (HPV)screeningScreeningPreoperative Care every 5 years for 10 years.
The decision to continue depends on whether the life expectancyLife expectancyBased on known statistical data, the number of years which any person of a given age may reasonably expected to live.Population Pyramids is ≥ 10 years and a discussion with the individual.
May be discontinued in individuals who have had a total hysterectomy:
With cervixCervixThe uterus, cervix, and fallopian tubes are part of the internal female reproductive system. The most inferior portion of the uterus is the cervix, which connects the uterine cavity to the vagina. Externally, the cervix is lined by stratified squamous cells; however, the cervical canal is lined by columnar epithelium.Uterus, Cervix, and Fallopian Tubes: Anatomy removed for benignBenignFibroadenoma causes
Without a history of cervical cancerCervical cancerCervical cancer, or invasive cervical carcinoma (ICC), is the 3rd most common cancer in women in the world, with > 50% of the cases being fatal. In the United States, ICC is the 13th most common cancer and the cause of < 3% of all cancer deaths due to the slow progression of precursor lesions and, more importantly, effective cancer screening. Cervical Cancer or cervical intraepithelial neoplasia (CINCINAn increased tendency to acquire chromosome aberrations when various processes involved in chromosome replication, repair, or segregation are dysfunctional.Colorectal Cancer)
Women with a history of CINCINAn increased tendency to acquire chromosome aberrations when various processes involved in chromosome replication, repair, or segregation are dysfunctional.Colorectal Cancer after screeningScreeningPreoperative Care for 20 years post-surgery
Exceptions: patientsPatientsIndividuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures.Clinician–Patient Relationship with a history of cervical cancerCervical cancerCervical cancer, or invasive cervical carcinoma (ICC), is the 3rd most common cancer in women in the world, with > 50% of the cases being fatal. In the United States, ICC is the 13th most common cancer and the cause of < 3% of all cancer deaths due to the slow progression of precursor lesions and, more importantly, effective cancer screening. Cervical Cancer, HIVHIVAnti-HIV Drugs, or other immunocompromise
Pap test:
A speculum is inserted into the vagina to widen the area. Next, a brush is inserted into the vagina to collect cells from the cervix. The cells are checked under a microscope for signs of disease.
Image by Lecturio.
Colorectal cancerColorectal cancerColorectal cancer (CRC) is the 2nd leading cause of cancer-related deaths in the United States. Colorectal cancer is a heterogeneous disease that arises from genetic and epigenetic abnormalities, with influence from environmental factors. Colorectal Cancer[14]
76–85 years of age: selective screeningScreeningPreoperative Care (decision to continue based on individual preferences, prior screeningScreeningPreoperative Care results, and overall health status/comorbiditiesComorbiditiesThe presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.St. Louis Encephalitis Virus)
ScreeningScreeningPreoperative Care may be discontinued if the life expectancyLife expectancyBased on known statistical data, the number of years which any person of a given age may reasonably expected to live.Population Pyramids is < 10 years.
Stool DNADNAA deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).DNA Types and Structure (sDNA)-FIT test every 3 years
Flexible sigmoidoscopySigmoidoscopyEndoscopic examination, therapy or surgery of the sigmoid flexure.Colorectal Cancer Screening every 5 years (limited to the distal part of the colonColonThe large intestines constitute the last portion of the digestive system. The large intestine consists of the cecum, appendix, colon (with ascending, transverse, descending, and sigmoid segments), rectum, and anal canal. The primary function of the colon is to remove water and compact the stool prior to expulsion from the body via the rectum and anal canal. Colon, Cecum, and Appendix: Anatomy)
CT colonographyCT colonographyA non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.Colorectal Cancer Screening every 5 years
Representation of a colonoscopy
Image by Lecturio.
Lung cancerLung cancerLung cancer is the malignant transformation of lung tissue and the leading cause of cancer-related deaths. The majority of cases are associated with long-term smoking. The disease is generally classified histologically as either small cell lung cancer or non-small cell lung cancer. Symptoms include cough, dyspnea, weight loss, and chest discomfort. Lung Cancer[15]
50–80 years of age: annual screeningScreeningPreoperative Care using low-dose CT of the chest for the following individuals:
20 pack-year smokingSmokingWillful or deliberate act of inhaling and exhaling smoke from burning substances or agents held by hand.Interstitial Lung Diseases history
Life expectancyLife expectancyBased on known statistical data, the number of years which any person of a given age may reasonably expected to live.Population Pyramids is limited.
OsteoporosisOsteoporosisOsteoporosis refers to a decrease in bone mass and density leading to an increased number of fractures. There are 2 forms of osteoporosis: primary, which is commonly postmenopausal or senile; and secondary, which is a manifestation of immobilization, underlying medical disorders, or long-term use of certain medications. Osteoporosis[17,20]
Women ≥ 65 years of age: BoneBoneBone is a compact type of hardened connective tissue composed of bone cells, membranes, an extracellular mineralized matrix, and central bone marrow. The 2 primary types of bone are compact and spongy. Bones: Structure and Types mineral density (BMD) screeningScreeningPreoperative Care is recommended.
The USPSTF states that there is not enough evidence to support screeningScreeningPreoperative Care in men.
The most commonly used test is the central dual-energy X-ray absorptiometryDual-Energy X-Ray AbsorptiometryOsteoporosis (DXA) of the hip and lumbar spineSpineThe human spine, or vertebral column, is the most important anatomical and functional axis of the human body. It consists of 7 cervical vertebrae, 12 thoracic vertebrae, and 5 lumbar vertebrae and is limited cranially by the skull and caudally by the sacrum.Vertebral Column: Anatomy.
Recommendations for calciumCalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Electrolytes 1,200 mg/day and vitamin DVitamin DA vitamin that includes both cholecalciferols and ergocalciferols, which have the common effect of preventing or curing rickets in animals. It can also be viewed as a hormone since it can be formed in skin by action of ultraviolet rays upon the precursors, 7-dehydrocholesterol and ergosterol, and acts on vitamin D receptors to regulate calcium in opposition to parathyroid hormone.Fat-soluble Vitamins and their Deficiencies 800 IU/day between diet and supplementation are not universally agreed upon.
ProstateProstateThe prostate is a gland in the male reproductive system. The gland surrounds the bladder neck and a portion of the urethra. The prostate is an exocrine gland that produces a weakly acidic secretion, which accounts for roughly 20% of the seminal fluid. cancer[6,12,26]
2nd-most common cancer diagnosis in men; however, most men will die of another cause due to the typically slow growth of prostateProstateThe prostate is a gland in the male reproductive system. The gland surrounds the bladder neck and a portion of the urethra. The prostate is an exocrine gland that produces a weakly acidic secretion, which accounts for roughly 20% of the seminal fluid. cancer. Thus, screeningScreeningPreoperative Care is controversial.
Men ages 55‒69 years:
Decision to screen is based on preferences, risk factors, and potential risks/benefits.
If elected, a blood test to detect PSAPSAA glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.Prostate Cancer alone is recommended as a screeningScreeningPreoperative Care strategy every 1‒2 years.
Digital rectal examinationDigital Rectal ExaminationA physical examination in which the qualified health care worker inserts a lubricated, gloved finger of one hand into the rectum and may use the other hand to press on the lower abdomen or pelvic area to palpate for abnormalities in the lower rectum, and nearby organs or tissues. The method is commonly used to check the lower rectum, the prostate gland in men, and the uterus and ovaries in women.Prostate Cancer Screening (DREDREA physical examination in which the qualified health care worker inserts a lubricated, gloved finger of one hand into the rectum and may use the other hand to press on the lower abdomen or pelvic area to palpate for abnormalities in the lower rectum, and nearby organs or tissues. The method is commonly used to check the lower rectum, the prostate gland in men, and the uterus and ovaries in women.Prostate Cancer Screening) is not recommended as a screeningScreeningPreoperative Care method with or without a PSAPSAA glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.Prostate Cancer test.
Age ≥ 70 years: PSAPSAA glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.Prostate CancerscreeningScreeningPreoperative Care is not recommended.
Depiction of prostate cancer pressing on the urethra (urinary symptoms result)
Herpes zosterHerpes ZosterVaricella-zoster virus (VZV) is a linear, double-stranded DNA virus in the Herpesviridae family. Shingles (also known as herpes zoster) is more common in adults and occurs due to the reactivation of VZV. Varicella-Zoster Virus/ChickenpoxvaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination[1,27]
CDC recommends the recombinant zoster vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination (RZV) for people ≥ 50 years of age todecrease the risk of developing herpes zosterHerpes ZosterVaricella-zoster virus (VZV) is a linear, double-stranded DNA virus in the Herpesviridae family. Shingles (also known as herpes zoster) is more common in adults and occurs due to the reactivation of VZV. Varicella-Zoster Virus/Chickenpox (shinglesShinglesVaricella-zoster virus (VZV) is a linear, double-stranded DNA virus in the Herpesviridae family. Shingles (also known as herpes zoster) is more common in adults and occurs due to the reactivation of VZV. Varicella-Zoster Virus/Chickenpox) and postherpetic neuralgiaPostherpetic neuralgiaPain in nerves, frequently involving facial skin, resulting from the activation the latent varicella-zoster virus. The two forms of the condition preceding the pain are herpes zoster oticus; and herpes zoster ophthalmicus. Following the healing of the rashes and blisters, the pain sometimes persists.Herpes Zoster (Shingles).
VaccinationVaccinationVaccination is the administration of a substance to induce the immune system to develop protection against a disease. Unlike passive immunization, which involves the administration of pre-performed antibodies, active immunization constitutes the administration of a vaccine to stimulate the body to produce its own antibodies.Vaccination should be performed irrespective of previous vaccinationVaccinationVaccination is the administration of a substance to induce the immune system to develop protection against a disease. Unlike passive immunization, which involves the administration of pre-performed antibodies, active immunization constitutes the administration of a vaccine to stimulate the body to produce its own antibodies.Vaccination status or disease history.
VaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination given in 2 doses:
2nd dose typically 2–6 months after the 1st
In immunocompromisedimmunocompromisedA human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation.Gastroenteritis individuals, 2nd dose 1–2 months after the 1st
Individuals who previously received the live attenuated vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination (Zostavax; not available since 2020) should be given the recombinant zoster vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination ≥ 5 years later.
InfluenzaInfluenzaInfluenza viruses are members of the Orthomyxoviridae family and the causative organisms of influenza, a highly contagious febrile respiratory disease. There are 3 primary influenza viruses (A, B, and C) and various subtypes, which are classified based on their virulent surface antigens, hemagglutinin (HA) and neuraminidase (NA). Influenza typically presents with a fever, myalgia, headache, and symptoms of an upper respiratory infection. Influenza Viruses/InfluenzavaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination[29]
> 90% of influenza-related deaths occur in individuals > 60 years of age.
InfluenzaInfluenzaInfluenza viruses are members of the Orthomyxoviridae family and the causative organisms of influenza, a highly contagious febrile respiratory disease. There are 3 primary influenza viruses (A, B, and C) and various subtypes, which are classified based on their virulent surface antigens, hemagglutinin (HA) and neuraminidase (NA). Influenza typically presents with a fever, myalgia, headache, and symptoms of an upper respiratory infection. Influenza Viruses/InfluenzavaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination should be given to all adults annually unless there is a history of allergic reactionsAllergic ReactionsType I hypersensitivity reaction against plasma proteins in donor bloodTransfusion Reactions to vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination components.
Advisory Committee on Immunization Practices (ACIP) 2022 recommendations for adults ages ≥ 65 years:
Quadrivalent high-dose or adjuvanted inactivated influenzaInfluenzaInfluenza viruses are members of the Orthomyxoviridae family and the causative organisms of influenza, a highly contagious febrile respiratory disease. There are 3 primary influenza viruses (A, B, and C) and various subtypes, which are classified based on their virulent surface antigens, hemagglutinin (HA) and neuraminidase (NA). Influenza typically presents with a fever, myalgia, headache, and symptoms of an upper respiratory infection. Influenza Viruses/InfluenzavaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination, OR
Quadrivalent recombinant influenzaInfluenzaInfluenza viruses are members of the Orthomyxoviridae family and the causative organisms of influenza, a highly contagious febrile respiratory disease. There are 3 primary influenza viruses (A, B, and C) and various subtypes, which are classified based on their virulent surface antigens, hemagglutinin (HA) and neuraminidase (NA). Influenza typically presents with a fever, myalgia, headache, and symptoms of an upper respiratory infection. Influenza Viruses/InfluenzavaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination
Pneumococcal vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination[9,21]
Reduces the risk of pneumococcal infectionsInfectionsInvasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.Chronic Granulomatous Disease, particularly with StreptococcusStreptococcusStreptococcus is one of the two medically important genera of gram-positive cocci, the other being Staphylococcus. Streptococci are identified as different species on blood agar on the basis of their hemolytic pattern and sensitivity to optochin and bacitracin. There are many pathogenic species of streptococci, including S. pyogenes, S. agalactiae, S. pneumoniae, and the viridans streptococci.Streptococcus pneumoniae,which is theleading cause of bacterial pneumoniaPneumoniaPneumonia or pulmonary inflammation is an acute or chronic inflammation of lung tissue. Causes include infection with bacteria, viruses, or fungi. In more rare cases, pneumonia can also be caused through toxic triggers through inhalation of toxic substances, immunological processes, or in the course of radiotherapy.Pneumonia
In all immunocompetent adults ≥ 50 years of age (new recommendations in OctOCTMacular Degeneration 2024):[21]
For individuals with no previous pneumococcal vaccines received (or vaccinationVaccinationVaccination is the administration of a substance to induce the immune system to develop protection against a disease. Unlike passive immunization, which involves the administration of pre-performed antibodies, active immunization constitutes the administration of a vaccine to stimulate the body to produce its own antibodies.Vaccination status unknown), administer:
1 dose of pneumococcal conjugate vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination (PCV) as PCV20 (alone), or
1 dose of PCV15 followed by pneumococcal polysaccharide vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination (PPSV) as PPSV23 at least 12 months later (8 weeks in immunocompromisedimmunocompromisedA human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation.GastroenteritispatientsPatientsIndividuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures.Clinician–Patient Relationship)
For individuals who already received PPSV23 only: give either PCV20 or PCV15 at least 12 months after PPSV23 dose.
For individuals who already received PCV13 only: complete the previously recommended PPSV23 series
TetanusTetanusTetanus is a bacterial infection caused by Clostridium tetani, a gram-positive obligate anaerobic bacterium commonly found in soil that enters the body through a contaminated wound. C. tetani produces a neurotoxin that blocks the release of inhibitory neurotransmitters and causes prolonged tonic muscle contractions. Tetanus and diphtheriaDiphtheriaDiphtheria is an infectious disease caused by Corynebacterium diphtheriae that most often results in respiratory disease with membranous inflammation of the pharynx, sore throat, fever, swollen glands, and weakness. The hallmark sign is a sheet of thick, gray material covering the back of the throat. Diphtheria toxoids (Td) or Tdap[5]
Approximately 60% of all tetanusTetanusTetanus is a bacterial infection caused by Clostridium tetani, a gram-positive obligate anaerobic bacterium commonly found in soil that enters the body through a contaminated wound. C. tetani produces a neurotoxin that blocks the release of inhibitory neurotransmitters and causes prolonged tonic muscle contractions. Tetanus cases in the US occur in individuals > 60 years of age.
Vaccines:
Tdap (tetanusTetanusTetanus is a bacterial infection caused by Clostridium tetani, a gram-positive obligate anaerobic bacterium commonly found in soil that enters the body through a contaminated wound. C. tetani produces a neurotoxin that blocks the release of inhibitory neurotransmitters and causes prolonged tonic muscle contractions. TetanustoxoidToxoidPreparations of pathogenic organisms or their derivatives made nontoxic and intended for active immunologic prophylaxis. They include deactivated toxins. Anatoxin toxoids are distinct from anatoxins that are tropanes found in cyanobacteria.Vaccination, reduced diphtheriaDiphtheriaDiphtheria is an infectious disease caused by Corynebacterium diphtheriae that most often results in respiratory disease with membranous inflammation of the pharynx, sore throat, fever, swollen glands, and weakness. The hallmark sign is a sheet of thick, gray material covering the back of the throat. DiphtheriatoxoidToxoidPreparations of pathogenic organisms or their derivatives made nontoxic and intended for active immunologic prophylaxis. They include deactivated toxins. Anatoxin toxoids are distinct from anatoxins that are tropanes found in cyanobacteria.Vaccination, and acellular pertussisPertussisPertussis, or whooping cough, is a potentially life-threatening highly contagious bacterial infection of the respiratory tract caused by Bordetella pertussis. The disease has 3 clinical stages, the second and third of which are characterized by an intense paroxysmal cough, an inspiratory whoop, and post-tussive vomiting. Pertussis (Whooping Cough))
Td
In the US:
Tdap or Td is given intramuscularly every 10 years to all adults with complete prior immunization to tetanusTetanusTetanus is a bacterial infection caused by Clostridium tetani, a gram-positive obligate anaerobic bacterium commonly found in soil that enters the body through a contaminated wound. C. tetani produces a neurotoxin that blocks the release of inhibitory neurotransmitters and causes prolonged tonic muscle contractions. Tetanus and diphtheriaDiphtheriaDiphtheria is an infectious disease caused by Corynebacterium diphtheriae that most often results in respiratory disease with membranous inflammation of the pharynx, sore throat, fever, swollen glands, and weakness. The hallmark sign is a sheet of thick, gray material covering the back of the throat. Diphtheria.
If an adult has not been vaccinated against tetanusTetanusTetanus is a bacterial infection caused by Clostridium tetani, a gram-positive obligate anaerobic bacterium commonly found in soil that enters the body through a contaminated wound. C. tetani produces a neurotoxin that blocks the release of inhibitory neurotransmitters and causes prolonged tonic muscle contractions. Tetanus and diphtheriaDiphtheriaDiphtheria is an infectious disease caused by Corynebacterium diphtheriae that most often results in respiratory disease with membranous inflammation of the pharynx, sore throat, fever, swollen glands, and weakness. The hallmark sign is a sheet of thick, gray material covering the back of the throat. Diphtheria, a 3-vaccine series is initiated with Tdap as the preferred 1st dose, followed by Td or Tdap.
Older adults:
Likely to have decreased antibodiesAntibodiesImmunoglobulins (Igs), also known as antibodies, are glycoprotein molecules produced by plasma cells that act in immune responses by recognizing and binding particular antigens. The various Ig classes are IgG (the most abundant), IgM, IgE, IgD, and IgA, which differ in their biologic features, structure, target specificity, and distribution.Immunoglobulins: Types and Functions either from not having received the initial vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination or the subsequent booster doses
Tdap is important for older adults, especially those in contact with children < 1 year of age:
Tdap may be given once instead of the Td booster.
Tdap can be administered regardless of the interval since the last Td booster.
Respiratory syncytial virusRespiratory Syncytial VirusRespiratory syncytial virus (RSV) is an enveloped, single-stranded, linear, negative-sense RNA virus of the family Paramyxoviridae and the genus Orthopneumovirus. Two subtypes (A and B) are present in outbreaks, but type A causes more severe disease. Respiratory syncytial virus causes infections of the lungs and respiratory tract.Respiratory Syncytial VirusvaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination[31]
CDC recommends shared decision-making.
Approved for ages 60 years and older
COVID-19COVID-19Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that mainly affects the respiratory system but can also cause damage to other body systems (cardiovascular, gastrointestinal, renal, and central nervous systems).vaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination[32]
1 dose of a bivalent mRNAmRNARNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3′ end, referred to as the poly(a) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.RNA Types and StructurevaccineVaccineSuspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccination is recommended.
Individuals ≥ 65 years of age may receive an additional dose.
Monovalent mRNAmRNARNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3′ end, referred to as the poly(a) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.RNA Types and Structure vaccines are no longer recommended.
Routine vaccination for adults:
Individuals with risk factors may require additional vaccinations or alterations in dosing schedule.
Tdap: tetanus, diphtheria, and acellular pertussis vaccination
Td: tetanus and diphtheria vaccination
HPV: human papillomavirus vaccination
HBV: hepatitis B virus vaccination
COVID-19: coronavirus disease 2019 vaccination (bivalent)
RZV: recombinant zoster vaccination
PCV: pneumococcal conjugate vaccination
*If not previously vaccinated
**If PCV15 is given, should be followed PPSV23 (pneumococcal polysaccharide vaccination)
Image by Lecturio.
Functional Assessment
Functional status[19]
Functional status is divided into 3 levels of ADLs:
Basic ADLs: self-care tasks such as bathing, dressing, feeding, and toileting
Instrumental ADLs (IADLs): complex skills to maintain independence such as driving, preparing meals, shopping, managing finances, and performing housework
Advanced ADLs: ability to fulfill various societal and familial roles and participate in recreational and occupational tasks
Hearing lossHearing lossHearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss:
3rd-most common chronic condition (after hypertensionHypertensionHypertension, or high blood pressure, is a common disease that manifests as elevated systemic arterial pressures. Hypertension is most often asymptomatic and is found incidentally as part of a routine physical examination or during triage for an unrelated medical encounter. Hypertension and arthritisArthritisAcute or chronic inflammation of joints.Osteoarthritis) among older adults in the US
Associated with cognitive decline, depression, social isolation, and functional disabilityDisabilityDetermination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for social security and workman’s compensation benefits.ABCDE Assessment
Sensorineural hearing lossSensorineural hearing lossHearing loss resulting from damage to the cochlea and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the auditory nerve and its connections in the brainstem.Hearing Loss is caused by natural aging of the auditory system.
The USPSTF has no recommendations for or against screeningScreeningPreoperative Care for hearing lossHearing lossHearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss in asymptomatic older adults.
Clinically recommended screeningScreeningPreoperative Care for hearing lossHearing lossHearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss in individuals ≥ 65 years of age:
Pure tone audiometryAudiometryThe testing of the acuity of the sense of hearing to determine the thresholds of the loWest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 hz are used to test air conduction thresholds and the frequencies between 250 and 4000 hz are used to test bone conduction thresholds.Ménière Disease:
Gold standard to screen for hearing lossHearing lossHearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss
Not readily available in primary care offices
Whispered-voice test:
Stand behind the individual (to prevent them from lip-reading) and mask the hearing in 1 ear.
A sequence of letters and numbers is whispered and the individual is asked to repeat them.
Refer to otolaryngology for any failed hearing test, chronic otitis media, and sudden hearing lossHearing lossHearing loss, also known as hearing impairment, is any degree of impairment in the ability to apprehend sound as determined by audiometry to be below normal hearing thresholds. Clinical presentation may occur at birth or as a gradual loss of hearing with age, including a short-term or sudden loss at any point. Hearing Loss.
Older adults are at a higher risk of visual impairments from conditions such as macular degenerationMacular degenerationAge-related macular degeneration (AMD) is visual impairment due to changes in the macula, the area responsible for high-acuity vision. It is marked by central vision loss with peripheral vision relatively spared. Risk factors include advanced age, smoking, family history, and cardiovascular disease.Macular Degeneration and cataracts.
Clinically, visionVisionOphthalmic Exam assessment is recommended for individuals with visual complaints, recent cognitive decline, functional impairments, or falls.
Falls[7,10,28]
An important cause of morbidityMorbidityThe proportion of patients with a particular disease during a given year per given unit of population.Measures of Health Status and mortalityMortalityAll deaths reported in a given population.Measures of Health Status among older adults
Approximately ⅓ of community-dwelling older adults > 65 years of age have a fall each year.
Evaluate the risk of falls:
Tinetti assessment tool:
Also called Performance-Oriented Mobility Assessment (POMA) tool
Ask the individual sitting on a chair to stand, walk 10 feet forward, turn around, walk back, and sit down.
In general, ≥ 13.5 seconds suggests a high risk of falls.
Factors affecting results (e.g., age, joint problems, underlying conditions such as Parkinson’s disease) should be considered during the assessment.
Prevention:
PT and targeted training activity
Vitamin DVitamin DA vitamin that includes both cholecalciferols and ergocalciferols, which have the common effect of preventing or curing rickets in animals. It can also be viewed as a hormone since it can be formed in skin by action of ultraviolet rays upon the precursors, 7-dehydrocholesterol and ergosterol, and acts on vitamin D receptors to regulate calcium in opposition to parathyroid hormone.Fat-soluble Vitamins and their Deficiencies supplementation
Securing the household environment (e.g., no clutter or loose rugs)
Use of assistive devices and equipment (e.g., walkers, bedside commode, shower chair, grab bars)
Urinary incontinenceUrinary incontinenceUrinary incontinence (UI) is involuntary loss of bladder control or unintentional voiding, which represents a hygienic or social problem to the patient. Urinary incontinence is a symptom, a sign, and a disorder. The 5 types of UI include stress, urge, mixed, overflow, and functional.Urinary Incontinence[5]
Obtain a targeted history and conduct an examination:
Inquire about the presence or absence of urinary incontinenceUrinary incontinenceUrinary incontinence (UI) is involuntary loss of bladder control or unintentional voiding, which represents a hygienic or social problem to the patient. Urinary incontinence is a symptom, a sign, and a disorder. The 5 types of UI include stress, urge, mixed, overflow, and functional.Urinary Incontinence biannually.
Determine the onset of urinary incontinenceUrinary incontinenceUrinary incontinence (UI) is involuntary loss of bladder control or unintentional voiding, which represents a hygienic or social problem to the patient. Urinary incontinence is a symptom, a sign, and a disorder. The 5 types of UI include stress, urge, mixed, overflow, and functional.Urinary Incontinence (acute or chronic), type (e.g., urge, stress, overflow, mixed), and precipitating factors (e.g., cough, medications).
Examine:
For signs of fluid overload
Pelvic (genital and rectal) area
Neurologic evaluation
Urine and blood tests as indicated, depending on the presenting factors
Limited resources directly impact an individual’s health.
Provide information regarding the availability of assistance for older adults in the community (e.g., food pantries, centers for seniors, organizations helping with prescriptions).
Elder abuse[5]
Up to 8% of older adults are affected by elder abuse.
USPSTF: Ask older individuals specific questions about abuse.
Further inquiry and referral to social services are required if the individual exhibits the following signs of abuse and/or neglectNeglectChild Abuse:
Contusions, burnsBurnsA burn is a type of injury to the skin and deeper tissues caused by exposure to heat, electricity, chemicals, friction, or radiation. Burns are classified according to their depth as superficial (1st-degree), partial-thickness (2nd-degree), full-thickness (3rd-degree), and 4th-degree burns. Burns, bite marks
Genital or rectal trauma
Pressure ulcers
BMIBMIAn indicator of body density as determined by the relationship of body weight to body height. Bmi=weight (kg)/height squared (m2). Bmi correlates with body fat (adipose tissue). Their relationship varies with age and gender. For adults, bmi falls into these categories: below 18. 5 (underweight); 18. 5-24. 9 (normal); 25. 0-29. 9 (overweight); 30. 0 and above (obese).Obesity < 17.5 (without clinical explanation)
Advance directivesAdvance DirectivesThe term advance directive (AD) refers to treatment preferences and/or the designation of a surrogate decision-maker in the event that a person becomes unable to make medical decisions on their own behalf. Advance directives represent the ethical principle of autonomy and may take the form of a living will, health care proxy, durable power of attorney for health care (DPAHC), and/or a physician’s order for life-sustaining treatment (POLST). Advance Directives
It is important to have discussions with older adults regarding advance care directives while they still have the cognitive capacity to make decisions.
Preferences regarding specific treatments, end-of-life interventions, and the appointed healthcare proxy should be documented.
These codes are used for routine health visits for older adults, including the Medicare “Welcome to Medicare” visit and subsequent Annual Wellness Visits, which focus on preventive care and screeningScreeningPreoperative Care.
Coding System
Code
Description
HCPCS
G0402
Initial preventive physical examination; face-to-face visit, services limited to new beneficiary during the first 12 months of Medicare enrollment
HCPCS
G0438
Annual wellness visit; includes a personalized prevention plan of service (PPPS), initial visit
HCPCS
G0439
Annual wellness visit, includes a personalized prevention plan of service (PPPS), subsequent visit
Common Procedures & Services:
These codes represent key services for geriatric patientsPatientsIndividuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures.Clinician–Patient Relationship, such as advance care planning discussions, screeningScreeningPreoperative Care for cognitive impairment, and assessing for fall risk.
Coding System
Code
Description
CPT
99497
Advance care planning including the explanation and discussion of advance directivesAdvance DirectivesThe term advance directive (AD) refers to treatment preferences and/or the designation of a surrogate decision-maker in the event that a person becomes unable to make medical decisions on their own behalf. Advance directives represent the ethical principle of autonomy and may take the form of a living will, health care proxy, durable power of attorney for health care (DPAHC), and/or a physician’s order for life-sustaining treatment (POLST). Advance Directives
Brief emotional/behavioral assessment with scoring and documentationDocumentationSystematic organization, storage, retrieval, and dissemination of specialized information, especially of a scientific or technical nature. It often involves authenticating or validating information.Advance Directives, per standardized instrument
Common Diagnoses:
These are examples of common chronic conditions documented and managed during geriatric care visits, such as hypertensionHypertensionHypertension, or high blood pressure, is a common disease that manifests as elevated systemic arterial pressures. Hypertension is most often asymptomatic and is found incidentally as part of a routine physical examination or during triage for an unrelated medical encounter. Hypertension, type 2 diabetesDiabetesDiabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin. Type 1 DM is diagnosed mostly in children and young adults as the result of autoimmune destruction of β cells in the pancreas and the resulting lack of insulin. Type 2 DM has a significant association with obesity and is characterized by insulin resistance.Diabetes Mellitus, osteoarthritisOsteoarthritisOsteoarthritis (OA) is the most common form of arthritis, and is due to cartilage destruction and changes of the subchondral bone. The risk of developing this disorder increases with age, obesity, and repetitive joint use or trauma. Patients develop gradual joint pain, stiffness lasting < 30 minutes, and decreased range of motion. Osteoarthritis, and dementiaDementiaMajor neurocognitive disorders (NCD), also known as dementia, are a group of diseases characterized by decline in a person’s memory and executive function. These disorders are progressive and persistent diseases that are the leading cause of disability among elderly people worldwide.Major Neurocognitive Disorders.
Coding System
Code
Description
ICD-10-CM
I10
Essential (primary) hypertensionHypertensionHypertension, or high blood pressure, is a common disease that manifests as elevated systemic arterial pressures. Hypertension is most often asymptomatic and is found incidentally as part of a routine physical examination or during triage for an unrelated medical encounter. Hypertension
ICD-10-CM
E11.9
Type 2 diabetesDiabetesDiabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin. Type 1 DM is diagnosed mostly in children and young adults as the result of autoimmune destruction of β cells in the pancreas and the resulting lack of insulin. Type 2 DM has a significant association with obesity and is characterized by insulin resistance.Diabetes Mellitus mellitus without complications
ICD-10-CM
M19.90
Unspecified osteoarthritisOsteoarthritisOsteoarthritis (OA) is the most common form of arthritis, and is due to cartilage destruction and changes of the subchondral bone. The risk of developing this disorder increases with age, obesity, and repetitive joint use or trauma. Patients develop gradual joint pain, stiffness lasting < 30 minutes, and decreased range of motion. Osteoarthritis, unspecified site
ICD-10-CM
F03.90
Unspecified dementiaDementiaMajor neurocognitive disorders (NCD), also known as dementia, are a group of diseases characterized by decline in a person’s memory and executive function. These disorders are progressive and persistent diseases that are the leading cause of disability among elderly people worldwide.Major Neurocognitive Disorders without behavioral disturbance
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